Perhaps most surprising to many women is that the pill has benefits that go beyond birth control. There are many options to choose from. Are Diabetic: Scientists still don't know for sure if the Pill can affect diabetic's blood sugar levels. Copyright. Smokers older than 35 also shouldn’t take birth control pills with estrogen. Is The Pill Safe To Take After 35? According to the chairman of the obstetrics and gynecology department at the University of Florida College, it is safe to take the contraceptive pill right up to menopause, as long as the woman is generally in good health, is not overweight and does not smoke. But there are some downsides to be aware of when you choose to go on birth control over the age of 55. It's my first time to use contraceptive pills (diane 35) I take my pills after my menstrual period and i just take it for only 2 days and have sex.. is there any possibility that i will get pregnant? It's news to many women. Start using these popular pills at the time of the first day of the menstruation. According to a 2011 review in Pediatrics, perimenopausal women on the pill have between a three- and five-fold increased risk of thrombosis compared to women under 35 who take the pill. Do not use if you are pregnant. Read more about contraceptive pills side effects, in relation to smokers. â¢ Got another question?